Serious Bug in NSX version 6.2.2 which leads to intermediately disconnection of the Guest VM.
The issue identified is due to the reason that NSX controller shows disconnected in the Web Client.
This leads to data path issues for VNIs handled by the disconnected controller.
VMware published the below KB article, explanining that the issue is due to the IPSec Re-keying feature which is disabled by default in the version 6.2.2
Recommendation is to disable the IPSec communication between the NSX controller or upgrade to version 6.2.4
I recommend to disable the IPSec rather than upgrading to the 6.2.4 version.